Andromeda Vadum - Voice Actor similar to Shipmaster Rtas Vadum
- Sangheili Marine Corps
- Barry Pepper (Marine Voice)
- Jeremy Renner (Marine Voice)
- Guy Pearce (Marine Voice)
- Brian Geraghty (Marine Voice)
- David Scully (Elite Voice)
- Norm Woodel (Elite Voice)
- Ronald Hippe (Elite Voice)
- Michael Konar - Keith David (Voice Actor of, The Arbiter)
- Major Josh Konaree - Barry Pepper
- Pvt. Zuka Chavamee - Sam Worthington
- Pvt. West (Sangheili) - Channing Tatum
- Field Master Lex Norsan - David Sobolov
- Elites - Robert Davi, David Scully, and Ron Hippe
- Xel Vaxum -
- Killax -
- Thug -
- Vax Xalum -
- Xeltive Thade -
- Lucas Kordin -
- Cpl. Jacobs -
- ONI Spartans
- Tristan Lorenzo -
- Michael Lorenzo -
- Ryan Kortiv -
- Ivan Mikhailov - Brian Bloom
- Fernando Hernandez - Shawn Roberts
- Dr. John Stenson - Iain Glen (portrayal) and Joseph Gordon-Levitt (Disk 3 and 4)
- Dr. Drake Kennedy - Adrien Brody (portrayal)
- Dr. Albert Simmons - David Hewlett (portrayal)
- Dr. Ashley Valentine - Sarah Polley (portrayal)
- Dark Ops Soldiers - David Sobolov
- Rebel Hitman Squads
- Rebel Snipers
- Rebel Commanders
- Rebel Soldiers
- Rebel Guards
- Ultranationalist Party Soldiers - Voice Actors from Modern Warfare series
- Viktor Ivanov - Clifton Collins Jr. (Voice)
- Kiril Morozov - Gene Vengerov-Markmann
- Lev Novikov - Sven Holmberg
- Vladimir Gorbachov - Sergio Castellitto (Keros: Chronicles) and Andrew Divoff (Keros: Resurrection)
- Dimitri Khrushchev - Eamon Hunt
- Dark Juggernauts - None
- Shadow Ninja's - (Voice actors who did the Ninja Gadien Black Spider Clan.)
- Khaled Al-Sahad - Gabriel Al-Rajhi
- Muhammad Saf-Halad - Igal Nagor
- Adam Savar - Khalid Abdalla
- The Al Kadhum (Iraqi Militia) - Gabriel Al-Rajhi (Iraqi languges)
- The Broadway Mafia - Any, with a Chicago or New York Accent
- Vincent Mancini - Voice similar to Red Grant (character)
- David Capone - Christian Bale
- The Architect - Smooth Male AI Voice with British Accent
- Anthony Capone - Hayden Christensen
- Kevin King - Christian Bale
- Jason Miller - Laurence Breuls (Some else with a similar voice is fine to)
- Matthew Davis - Michael Sheen
- Devourers (Parasites) - Unknown
- Freddy Krueger - Robert Englund (Voice)
- USAAF Command - Glenn Morshower
- ODST Command - Todd Alderman
- ODST and USAAF pilots - Sam Worthington
- ODST Soldiers - Curtis Jackson, Nolan North, and Alan Tudyk
- Pvt. James Connor (Playable Character for the Rangers) - Mark Wahlberg
- Pvt. Andrew Collen - David Scully
- Pvt. Daniel Scott - Adam Baldwin
- Pvt. Allen White - Alan Tudyk
- Pvt. Lewis Jones - Kevin Mckidd
- Sgt. Matt Wilson - Nathan Fillion
- Sgt. David Moore - Pete Stacker
- Sgt. Brian Bacon - Alan Tudyk
- Sgt. Jacob Price - Nolan North
- Sgt. John Stevens - Berry Pepper
- Lt. Dan Gonzalez - Andy McKaige
- Lt. Jordan Daniels -' 'Mikey Kelly
- Lt. Damian Reed - Michael Cudlitz
- Cpl. James Dunn - Berry Pepper
- Cpl. Ryan Vasquez - David Sobolov
- Cpl. Kevin Mendoza - Steve Downes
- Cmdr. Steve Ramirez - Sam Worthington